EDK
Editome Disease Knowledgebase
Anxiety disorder
| Disease name | Anxiety disorder |
|---|---|
| Classfication | Cognitive disorder |
| Related Enzyme(s) | |
| EFO | EFO:0006788 |
| DOID | 2030 |
| OMIM | |
| NCI | |
| Definition | Anxiety disorders are a group of mental disorders characterized by significant feelings of anxiety and fear.[2] Anxiety is a worry about future events, and fear is a reaction to current events.[2] These feelings may cause physical symptoms, such as a fast heart rate and shakiness. |
| Gene symbol | Species | Enzyme | Editing site(s) | Editing Type | PMID | RADAR | REDIportal | Description |
|---|---|---|---|---|---|---|---|---|
| GABRA-3 | Human | ADAR1;ADAR2 | 1 | G-to-A | GABAA receptors respond to anxiolytic drugs such as benzodiazepines and are thus important drug targets. I/M editing could be important in determining the mechanistic features that are responsible for the diversity of GABAA receptors and the variability in sensitivity to drugs. |
| Enzyme | Full Name | Location | Ensembl | Targets | Related Diseases | Aliases |
|---|---|---|---|---|---|---|
| ADAR1 | Adenosine deaminase, RNA specific | Chr1:154582057..154631560 |
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